Scientists from the Karolinska Institute in Sweden and the University of Lyon in France, after 13 years of observation of 54 men and women, came to the conclusion that people gain weight with age due to the characteristics of the body, in which the rate of lipid excretion simply slows down.
The study is published in the journal Nature Medicine, and is briefly described on the website of the Karolinska Institute. For 13 years, molecular biologists kept under observation 54 men and women who became participants in the experiment.
They monitored how lipid metabolism occurs in adipose tissue in the bodies of these people. Until now, the question of whether this process is constant throughout life has remained open.
New research provides an answer. Lipids are a large group of organic compounds that include fats and fat-like substances. In all subjects, regardless of whether they gained weight or lost weight over the past time, a decrease in lipid metabolism in adipose tissue was noted.
That is, they have decreased the rate at which lipids are removed from adipose tissue. You can compensate for the decrease in speed by reducing the amount of calories consumed, which has also been proven by the study.
Scientists calculated that those subjects who did not cut calories in their diets, on average, weighed 20 percent of their original weight. That is, people gain weight simply because their rate of lipid metabolism decreases.
The researchers also followed 41 women who underwent bariatric surgery. The analysis showed that their rate of lipid metabolism increased, which allowed them to keep their weight at the same level or even reduce it for four to seven years after the operation.
"These results indicate for the first time that the processes occurring in our adipose tissue regulate changes in body weight during aging in a way that is independent of other factors," says study co-author Peter Arner. "Our discovery will help create new ways to treat obesity. ".
Previous research has shown that exercise is one of the best ways to increase lipid turnover in adipose tissue. New research has confirmed this hypothesis as well.