Coronavirus vaccines may be less effective for obese people. This reason was identified in the journal Nature, scientists interviewed by Izvestia confirmed this data.
Maria Vedunova, director of the Institute of Biology and Biomedicine of the UNN, explained that overweight people have chronic immunodeficiency. In this regard, the effectiveness of vaccinations will be lower than that of people who do not experience such problems.
At the same time, Sergei Netesov, Corresponding Member of the Russian Academy of Sciences, Head of the Laboratory of Biotechnology and Virology at the Faculty of Natural Sciences of NSU, explained that the vaccine may be ineffective for obesity and for other reasons. In particular, the active ingredient of the vaccine does not spread through the body through the bloodstream, but "binds" in the fat layer.
Nikita Zhuravlev, an employee of the Laboratory for Analysis of Population Health Indicators and Digitalization of Health Care at MIPT, noted that studies of vaccines against influenza, hepatitis B and rabies have shown a decrease in the response in obese people compared to those with normal body mass index.
However, there is no official data, confirmed by research, on the ineffectiveness of coronavirus vaccines for people with obesity. Specialists will receive this information during clinical trials.
In October, the general director of the Almazov National Medical Research Center, Yevgeny Shlyakhto, said that the risk of death after coronavirus among obese Russians increases nine times. He also noted that the unfavorable development of the disease may in part be caused by a deficiency of vitamin D in the body.