The Mechanism Of Prolonging Youth And Life Is Revealed

The Mechanism Of Prolonging Youth And Life Is Revealed
The Mechanism Of Prolonging Youth And Life Is Revealed

Video: The Mechanism Of Prolonging Youth And Life Is Revealed

Video: Forever Young: Russian scientists reveal secret of eternal life (RT Documentary) 2022, November
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Scientists at the Ottawa Hospital Research Institute in Canada have uncovered a mechanism by which exercise can help delay biological aging. Experts published their review of the evidence of the benefits of physical activity in prolonging youth in the journal Open Biology.

The so-called satellite cells or myosatellites play a key role in the regeneration of skeletal muscles responsible for body movement. They are stem cells, that is, they ensure the growth of muscle tissue through division and differentiation - the process of transformation into a mature muscle cell. Under normal conditions, myosatellites are at rest, but with injury or exercise, they form muscle fibers. This leaves a certain number of satellite cells capable of returning back to an inactive state.

Scientists have found that with aging of muscles, which begins at about 30 years, prolonged rest of myosatellites turns out to be fatal for them. In this state, they are unable to effectively remove from themselves metabolic by-products that accumulate and become toxic, damaging the cell. Thus, stem cells enter an irreversible state in which division and differentiation becomes impossible. As a result, the muscle tissue's ability to regenerate is significantly impaired.

A middle-aged person loses, on average, 3-5 percent of muscle mass annually, and over a lifetime - about 30 percent. However, physical activity slows down the aging of skeletal muscle and improves regeneration. It enhances the activity and number of mitochondria - cellular organelles responsible for supplying the cell with energy and regulating metabolism. At the same time, even regular training does not prevent the loss of a certain amount of viable myosatellites.

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